Principles of Genetics

Daffodil International University Department of Genetic Engineering and Biotechnology Faculty of Health and Life Sciences B. Sc. (Hons.) in Genetic Engineering and Biotechnology Midterm Examination Fall 2026 Course Code: 0512-1201 Course Title: Principles of Genetics Level and Term: L1, T2 Section: 262-A Course Teacher Initials: AR Time: 1 Hour 30 Minutes Total Marks: 25 Answer the Following Questions: Marks 1 (a) Define phenotype, genotype, and variety with suitable examples. [CLO1, PLO1, C1] 3.0 (b) Illustrate Mendel's experiments on Pisum sativum, highlighting his experimental approach and major findings. [CLO1, PLO1, C5] 2.0 2 (a) Identify the major exceptions to Mendelian inheritance and provide one example of each. [CLO2, PLO2, C1] 3.0 (b) Compare Mendelian and non-Mendelian inheritance based on their inheritance patterns, genetic mechanisms, and phenotypic ratios. [CLO3, PLO1, C4] 2.0 3 (a) Analyze how incomplete dominance deviates from the classical Mendelian monohybrid ratio, using a suitable genetic cross and Punnett square. [CLO3, PLO1, C4] 2.0 (b) Construct a genetic cross and Punnett square to demonstrate how a homozygous recessive genotype at one locus masks the expression of another gene. [CLO3, PLO2, C3] 3.0 4 (a) Define pleiotropism. Explain the major features of pleiotropy with a suitable example. [CLO1, PLO1, C5] 2.0 (b) Define linkage group. Construct the linkage map of chromosome 1 and 3 of Drosophila melanogaster. [CLO3, PLO2, C6] 3.0 5 (a) Define a chromosome map and interpret the cytogenetic location 11p15.5, explaining the significance of each component of the notation. [CLO2, PLO2, C2] 3.0 (b) Explain multiple allelism and analyze the inheritance pattern resulting from a cross between a homozygous chinchilla rabbit and a heterozygous Himalayan rabbit, using a Punnett square. [CLO2, PLO2, C3] 2.0